Embryology

Embryogenesis

  • Zygote
  • Morula
  • Blastocyst
    • Embryoblast [Inner cell mass]
    • Trophoblast [Outer cell mass]
      • Cytotrophoblast
      • Syncitiotrophoblast

Embryonic Development

Week Milestones
1 Implantation
2 Bilaminar disc
3 Trilaminar disc
Gastrulation
Neurulation
4 Heart
Pharyngeal arches
Limb buds
5 Lens pit
Nasal pit
6 Hand plate
Foot plate
7 Finger rays
8 Fetal movement
10 Genitalia

Extraembryonic Membranes {CAYA}

Membrane Derivatives Remnant Markers
Chorion Placenta - hCG
Amnion Umbilical chord - AFP
Yolk sac Vitelline duct Meckel's diverticulum AFP
Allantois Allantoic duct Urachal diverticulum AFP

Ectoderm

Surface Ectoderm

  • Anterior pituitary
    [Adenohypophysis]
  • Epidermis
  • Lens
  • Mammary gland
  • Salivary gland
  • Sensory organs
  • Sweat gland
  • Urethra :: penile
  • Urogenital fold

Neuroectoderm :: Neural Tube

  • CNS neurons
  • CNS glial cells
    • Astrocytes
    • Ependymal cells
    • Oligodendrocytes
  • Olfactory nerve
  • Optic nerve
  • Pineal gland
  • Posterior pituitary
    [Neurohypophysis]
  • Retina

Neuroectoderm :: Neural Crest

  • Adrenal medulla
  • Endocardial cushions
  • Leptomeninges
  • Melanocytes
  • Odontoblasts
  • PNS ganglia
  • Schwann cells
  • Spiral membrane

Mesoderm

  • Adrenal cortex
  • Blood
  • Connective tissue
  • Cardiovascular
  • Dermis
  • Genital ducts
    • Mullerian duct
      [Paramesonephric duct]
    • Wolffian duct
      [Mesonephric duct]
  • Gonads
  • Kidney
  • Lymphatics
  • Muscle
  • Notochord
  • Serosa
    • Pleura
    • Pericardium
    • Peritoneum
  • Spleen

Endoderm

  • Eustachian tube
  • Gastrointestinal tract
  • Liver
  • Lung
  • Pancreas
  • Parathyroid
  • Thymus
  • Thyroid
    • Follicular cell
    • Parafollicular [C] cell
  • Urethra :: prostatic & membranous
  • Urinary bladder
  • Urogenital sinus

Pharyngeal Apparatus {CAP}

Component Origin
Cleft Ectoderm
Arch Mesoderm
Pouch Endoderm

Pharyngeal Cleft

  Derivatives
1 External auditory meatus
2
3
4
Cervical sinus
Pharyngeal cleft cyst

Pharyngeal Arch

  Bones & Cartilages Muscles Nerves
1 Zygomatic bone
Maxillary bone
Mandible
Meckel cartilage
Malleus
Incus
Masticatory muscles
Mylohyoid
Digastric muscle :: anterior belly
Tensor tympani
Tensor veli palatini
CN V3
2 Stapes
Styloid process
Hyoid :: lesser horn
Stapedius
Facial muscles
Digastric muscle :: posterior belly
Stylohyoid
CN VII
3 Hyoid :: greater horn Stylopharyngeus CN IX
4 Laryngeal cartilages Palatal muscles - Tensor veli palatini
Pharyngeal muscles - Stylopharyngeus
Levator veli palatini
Cricothyroid
CN X :: pharyngeal branch
CN X :: superior laryngeal nerve
6 Laryngeal cartilages Laryngeal muscles - Cricothyroid CN X :: recurrent laryngeal nerve

Pharyngeal Pouch

  Derivatives
1 Middle ear
Eustachian tube
2 Tonsil
3 Thymus
Inferior parathyroids
4 Superior parathyroids
Parafollicular [C] cells