Hematopoietic System

Hematopoiesis

Granules in Blood Cells

Cell Granule Contents
Neutrophil Specific granule Leukocyte alkaline phosphatase (LAP)
Collagenase
Lactoferrin
  Azurophilic granule Proteinases
Acid phosphatase
Myeloperoxidase
β-glucuronidase
Eosinophil Eosinophilic granule Histaminase
Major basic protein (MBP)
Eosinophil peroxidase
Eosinophil cationic protein
Basophil Basophilic granule Heparin
Histamine
Platelet α granule vWF
Fibrinogen
Fibronectin
Platelet factor 4 (PF4)
  Dense granule Calcium
ADP
Serotonin
Histamine

Erythropoiesis

Mnemonic Site
Young York sac
Liver Liver
Synthesizes Spleen
Blood Bone marrow

Heme Synthesis

Hemoglobin Genes

Oxygen-Hemoglobin Dissociation Curve

Causes of Right Shift {BAT-ACE}

  • 2,3-BPG
  • Altitude
  • Temperature
  • Acid
  • CO2
  • Exercise

WBC Differential Counts

Mnemonic Cell Ratio
Neutrophils Neutrophil 60%
Like Lymphocyte 30%
Making Monocyte 6%
Everything Eosinophil 3%
Better Basophil 1%

Coombs Tests